Run mysql_secure_installation ?

==== Required information ====
- iRedMail version: 0.9.2
- Store mail accounts in which backend (LDAP/MySQL/PGSQL):  MySQL
- Web server (Apache or Nginx): Ngnix
- Linux/BSD distribution name and version: Ubuntu 14.04
- Related log if you're reporting an issue:
====

It is safe to run Run mysql_secure_installation  and remove:

Remove anonymous users?
Disallow root login remotely?
Remove test database and access to it?

Also why doesn't iredmail script run mysql_secure_installation ?

Thanks